Sardine trimethylamine (Sardina pilchardus)a probable antagonist of the cerebral effect of alcohol

Abstract

Many people in various parts of the world suffer from the negative effect of alcohol, it lead to inappropriate ways of behavior in society, let alone, car accidents, crimes and social scourges. This study sought to describe the relationship between alcohol, trimethylamine (TMA) and choline through recently published articles that demonstrated that choline has an effect on alcohol in the same way that the TMA can affect the alcohol drinker. It is known that the smell of fish originates from TMA, which has a similar structure to choline, and from this basis we suggest this hypothesis. TMA is a part of the components of the human body that includes several functions, especially those related to synapses. Choline also has a greater importance in the human body, where it participates in its basic necessary processes, such as signal transmission and membrane formation, also, both choline and TMA are bound by metabolism processes. In an attempt by us to establish the relationship between TMA and alcohol, we compared both structures, that of choline and that of TMA, which further can confirm the validity of the above-mentioned hypothesis.